HSV-1 Quantisation from Rabbit Neural Tissues after Epinephrine-lnduced Reactivation

absolutely required to initiate pock formation. Studies currently in progress will examine the role of donor and recipient effector cells. Our findings demonstrate that sensitization to lymphocyte antigens may lead to allograft rejection against donor corneal endothelial cells, and this has important implications for human graft recipients who have received previous blood transfusions. This new, simplified model of corneal allograft rejection will permit controlled sensitization to a variety of corneal and histocompatibility antigens, which may be responsible for initiation of graft rejection. The model is ideal for studying the sensitization of isolated lymphocyte populations, and their interactions with cells of the corneal endothelium in vivo and allows for experimental manipulations during the sensitization phase, which may lead eventually to a means of completely abrogating the corneal allograft reaction.